Congratulations to the Year 3 BDCI Accelerator Grant Recipients!
We are thrilled to announce the recipients of the Year 3 BDCI Accelerator Grants! These grants aim to further cultivate the network of Emory researchers working at the critical intersection of chemistry, biology, and human health, and fund innovative, cross-disciplinary projects that align with the mission of the BDCI. This year’s proposals span three major units at Emory (ECAS, SOM, Winship Cancer Institute) and ten departments!
These six groups will receive $40,000 over the next year to complete the aims outlined in their proposal, with the ultimate goal of providing the preliminary data necessary to apply for larger, extramural funding. The 2022 projects — along with their principal investigators and co-investigators — that received Accelerator Grants are:
Nicholas Boulis + Yuhong Du
Targeting oxidative stress-induced tumor edge cells for therapeutic discovery in the minipig glioblastoma model
Craig Castellino + Erik Dreaden
Development of brain-penetrant inhibitors for PPM1D-altered high-grade pediatric brain tumors
Graeme Conn + Bill Wuest
Mechanism-based inhibition of oligoadenylate synthetase 1 (OAS1) gain-of-function
Eric Miller + Cynthia Derdeyn
Safer, longer-acting prodrugs of tenofovir that target HIV-enriched tissue
Stephen Pelly + Baek Kim + Dennis Liotta
Rational-based design of novel non-covalent SARS-CoV-2 main protease inhibitors
Renee Read + Steven Sloan
Drug target discovery with human organoid models of pediatric high-grade gliomas
Please join us in congratulating our awardees! We look forward to hearing their progress and seeing what exciting breakthroughs come as a result of their work!
Applications for the next round of Accelerator Grants will open Fall 2022. Stay tuned for updates.